Salicylic acid is known for its ability to relieve aches and pains and reduce fever. relief of fever, found in ancient times. It is used as an anti-inflammatory drug.
In modern medicine, salicylic acid and its derivatives are constituents of some rubefacient ( "skin-reddening") products. For example, methyl salicylate used as a liniment to relieve joint and muscle pain and choline salicylate used topically to relieve the pain of canker sores.
cotton soaked in salicylic acid can be used for chemical peels
As with other hydroxy acids, salicylic acid is the main ingredient in many skin care products for the treatment of seborrheic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis and warts.
Salicylic acid works as a keratolytic, comedolytic and bacteriostatic agents, causing the cells of the epidermis to shed more easily, opening the clogged pores and neutralize bacteria, preventing pores from clogging again and allow room for new cell growth.
Because of its effect on skin cells, salicylic acid used in some shampoos to treat dandruff. concentrated solution of salicylic acid can cause hyperpigmentation in people with darker skin types (Fitzpatrick phototypes IV, V, VI), without a broad spectrum sunblock.
bismuth subsalicylate, bismuth salts and salicylic acid, the active ingredient in the stomach relief aid such as Pepto-Bismol, is the main ingredient Kaopectate and "show anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotics".
Salicylic acid is used in the production of other medicines, including 4-aminosalicylic acid landetimide sandulpiride (via Salethamide).
In 2016, salicylic acid - and (more potent) diflunisal, cousin of aspirin - was shown to suppress the protein responsible for cell damage caused by inflammation
Salicylic acid has the formula C6H4 (OH) COOH, in which the OH group is ortho to the carboxyl group. It is also known as 2-hydroxybenzoic acid. It is soluble in water (2 g / L at 20 ° C). Aspirin (acetylsalicylic acid or ASA) can be made by esterification of phenolic hydroxyl group of salicylic acid with acetyl group of acetic anhydride or acetyl chloride. Salicylic acid can also be created by using the Kolbe-Schmitt reaction.
Salicylic acid is used as a food preservative, bactericidal and antiseptic.
Sodium salicylate is a useful phosphor in the vacuum ultraviolet, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm. Fluoresces in the blue at 420 nm. It is easy to put on a clean surface by spraying saturated salt solution in methanol followed by evaporation.